BDBM50016706 CHEMBL63139::Octahydro-indolizine-1,2,8-triol::Swainsonine::TRIDOLGOSIR::Tridolgosir

SMILES: [H][C@@]12[C@H](O)[C@H](O)CN1CCC[C@H]2O

InChI Key: InChIKey=FXUAIOOAOAVCGD-RYVOCIFZSA-N

Data: 1 IC50

PDB links: 5 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50016706   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-mannosidase 2C1 (Rattus norvegicus)	BDBM50016706 (CHEMBL63139 | Octahydro-indolizine-1,2,8-triol | S...) Show SMILES [H][C@@]12[C@H](O)[C@H](O)CN1CCC[C@H]2O Show InChI InChI=1S/C8H15NO3/c10-5-2-1-3-9-4-6(11)8(12)7(5)9/h5-8,10-12H,1-4H2/t5-,6?,7-,8?/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
CSIRO Division of Chemicals and Polymers Curated by ChEMBL					Assay Description Inhibitory activity against Mannosidase in jack bean (Canavalia ensiformis)				J Med Chem 32: 2084-9 (1989) BindingDB Entry DOI: 10.7270/Q2TQ6246
					More data for this Ligand-Target Pair