BDBM50016806 CHEMBL1236552
SMILES: O[C@H]1C[C@@H](O[C@@H]1COP(O)(O)=O)n1cc(C=O)c(=O)[nH]c1=O
InChI Key: InChIKey=LVYWYEBCBRVIEG-XLPZGREQSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thymidylate Synthase (TS) (Lactobacillus casei) | BDBM50016806 (CHEMBL1236552) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of amethopterin-resistant Lactobacillus casei thymidylate synthetase-catalyzed dTMP formation using dUMP as substrate by spectrophotometri... | J Med Chem 20: 1469-73 (1977) BindingDB Entry DOI: 10.7270/Q2P55Q1K | |||||||||||
More data for this Ligand-Target Pair |