null

SMILES: CN(C1CCCCCC1)C(=O)c1csc(CNS(=O)(=O)c2cccc(Cl)c2)n1

InChI Key: InChIKey=NYFXYYYKZNDWTF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50017010   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50017010 (CHEMBL3287024) Show SMILES CN(C1CCCCCC1)C(=O)c1csc(CNS(=O)(=O)c2cccc(Cl)c2)n1 Show InChI InChI=1S/C19H24ClN3O3S2/c1-23(15-8-4-2-3-5-9-15)19(24)17-13-27-18(22-17)12-21-28(25,26)16-10-6-7-14(20)11-16/h6-7,10-11,13,15,21H,2-5,8-9,12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1				J Med Chem 57: 4466-86 (2014) Article DOI: 10.1021/jm4014746 BindingDB Entry DOI: 10.7270/Q280546B
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50017010 (CHEMBL3287024) Show SMILES CN(C1CCCCCC1)C(=O)c1csc(CNS(=O)(=O)c2cccc(Cl)c2)n1 Show InChI InChI=1S/C19H24ClN3O3S2/c1-23(15-8-4-2-3-5-9-15)19(24)17-13-27-18(22-17)12-21-28(25,26)16-10-6-7-14(20)11-16/h6-7,10-11,13,15,21H,2-5,8-9,12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	307	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD1				J Med Chem 57: 4466-86 (2014) Article DOI: 10.1021/jm4014746 BindingDB Entry DOI: 10.7270/Q280546B
					More data for this Ligand-Target Pair