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BDBM50017140 CHEMBL3287062

SMILES: CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O

InChI Key: InChIKey=QAQKCNLBMSOGFO-QORCZRPOSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50017140   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))		BDBM50017140
PNG
(CHEMBL3287062)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r|
Show InChI InChI=1S/C31H46N14O5/c1-17(46)42-25(13-19-15-37-16-41-19)29(50)44-22(8-4-10-38-30(33)34)27(48)43-23(9-5-11-39-31(35)36)28(49)45-24(26(32)47)12-18-14-40-21-7-3-2-6-20(18)21/h2-3,6-7,14-16,22-25,40H,4-5,8-13H2,1H3,(H2,32,47)(H,37,41)(H,42,46)(H,43,48)(H,44,50)(H,45,49)(H4,33,34,38)(H4,35,36,39)/t22-,23-,24-,25-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 75n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Agonist activity at wild type human melanocortin-4 receptor expressed in HEK293 cells co-transfected with CRE/beta-galactosidase reporter gene assess...

J Med Chem 57: 4615-28 (2014)


Article DOI: 10.1021/jm500064t
BindingDB Entry DOI: 10.7270/Q2VQ347J
More data for this
Ligand-Target Pair