BDBM50017254 CHEMBL3287696

SMILES: Cc1c(O)c(ccc1OCCCCOCOc1ccc(cc1)C(O)=O)C(=O)CC1CCCC1

InChI Key: InChIKey=WIKSLWGWAGNVMC-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50017254   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017254 (CHEMBL3287696) Show SMILES Cc1c(O)c(ccc1OCCCCOCOc1ccc(cc1)C(O)=O)C(=O)CC1CCCC1 Show InChI InChI=1S/C26H32O7/c1-18-24(13-12-22(25(18)28)23(27)16-19-6-2-3-7-19)32-15-5-4-14-31-17-33-21-10-8-20(9-11-21)26(29)30/h8-13,19,28H,2-7,14-17H2,1H3,(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	228	n/a	n/a	n/a	n/a
Sanford-Burnham Medical Research Institute Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR2 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced thallium flux incubated...				J Med Chem 57: 4154-72 (2014) Article DOI: 10.1021/jm5000563 BindingDB Entry DOI: 10.7270/Q2GH9KH9
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017254 (CHEMBL3287696) Show SMILES Cc1c(O)c(ccc1OCCCCOCOc1ccc(cc1)C(O)=O)C(=O)CC1CCCC1 Show InChI InChI=1S/C26H32O7/c1-18-24(13-12-22(25(18)28)23(27)16-19-6-2-3-7-19)32-15-5-4-14-31-17-33-21-10-8-20(9-11-21)26(29)30/h8-13,19,28H,2-7,14-17H2,1H3,(H,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.91E+3	n/a	n/a	n/a	n/a
Sanford-Burnham Medical Research Institute Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR3 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced thallium flux incubated...				J Med Chem 57: 4154-72 (2014) Article DOI: 10.1021/jm5000563 BindingDB Entry DOI: 10.7270/Q2GH9KH9
					More data for this Ligand-Target Pair