BDBM50017451 1-(2-Propyl-phenyl)-piperazine::CHEMBL9870

SMILES: CCCc1ccccc1N1CCNCC1

InChI Key: InChIKey=FHIDPEUFJOUCRS-UHFFFAOYSA-N

Data: 7 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50017451   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 1B/1D receptor (Rattus norvegicus (Rat))	BDBM50017451 (1-(2-Propyl-phenyl)-piperazine | CHEMBL9870) Show SMILES CCCc1ccccc1N1CCNCC1 Show InChI InChI=1S/C13H20N2/c1-2-5-12-6-3-4-7-13(12)15-10-8-14-9-11-15/h3-4,6-7,14H,2,5,8-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical and Janssen Research Foundation Worldwide Curated by ChEMBL					Assay Description Binding affinity at rat 5-hydroxytryptamine 1B receptor by [3H]-5-HT displacement.				J Med Chem 32: 1052-6 (1989) BindingDB Entry DOI: 10.7270/Q2HD7TNH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50017451 (1-(2-Propyl-phenyl)-piperazine | CHEMBL9870) Show SMILES CCCc1ccccc1N1CCNCC1 Show InChI InChI=1S/C13H20N2/c1-2-5-12-6-3-4-7-13(12)15-10-8-14-9-11-15/h3-4,6-7,14H,2,5,8-11H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical and Janssen Research Foundation Worldwide Curated by ChEMBL					Assay Description Binding affinity at rat 5-hydroxytryptamine 1A receptor by [3H]-WB-4101 displacement.				J Med Chem 32: 1052-6 (1989) BindingDB Entry DOI: 10.7270/Q2HD7TNH
					More data for this Ligand-Target Pair
Serotonin 1 (5-HT1) receptor (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)	BDBM50017451 (1-(2-Propyl-phenyl)-piperazine | CHEMBL9870) Show SMILES CCCc1ccccc1N1CCNCC1 Show InChI InChI=1S/C13H20N2/c1-2-5-12-6-3-4-7-13(12)15-10-8-14-9-11-15/h3-4,6-7,14H,2,5,8-11H2,1H3	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical and Janssen Research Foundation Worldwide Curated by ChEMBL					Assay Description Binding affinity determined in radioreceptor binding assay by using [3H]5-HT radioligand against 5-hydroxytryptamine 1 receptor				J Med Chem 32: 1052-6 (1989) BindingDB Entry DOI: 10.7270/Q2HD7TNH
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50017451 (1-(2-Propyl-phenyl)-piperazine | CHEMBL9870) Show SMILES CCCc1ccccc1N1CCNCC1 Show InChI InChI=1S/C13H20N2/c1-2-5-12-6-3-4-7-13(12)15-10-8-14-9-11-15/h3-4,6-7,14H,2,5,8-11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical and Janssen Research Foundation Worldwide Curated by ChEMBL					Assay Description Binding affinity against rat Alpha-1 adrenergic receptor.				J Med Chem 32: 1052-6 (1989) BindingDB Entry DOI: 10.7270/Q2HD7TNH
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50017451 (1-(2-Propyl-phenyl)-piperazine | CHEMBL9870) Show SMILES CCCc1ccccc1N1CCNCC1 Show InChI InChI=1S/C13H20N2/c1-2-5-12-6-3-4-7-13(12)15-10-8-14-9-11-15/h3-4,6-7,14H,2,5,8-11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	232	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical and Janssen Research Foundation Worldwide Curated by ChEMBL					Assay Description Binding affinity at rat 5-hydroxytryptamine 2 receptor by [3H]ketanserin displacement.				J Med Chem 32: 1052-6 (1989) BindingDB Entry DOI: 10.7270/Q2HD7TNH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50017451 (1-(2-Propyl-phenyl)-piperazine | CHEMBL9870) Show SMILES CCCc1ccccc1N1CCNCC1 Show InChI InChI=1S/C13H20N2/c1-2-5-12-6-3-4-7-13(12)15-10-8-14-9-11-15/h3-4,6-7,14H,2,5,8-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	379	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical and Janssen Research Foundation Worldwide Curated by ChEMBL					Assay Description Binding affinity against rat Dopamine receptor D2.				J Med Chem 32: 1052-6 (1989) BindingDB Entry DOI: 10.7270/Q2HD7TNH
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50017451 (1-(2-Propyl-phenyl)-piperazine | CHEMBL9870) Show SMILES CCCc1ccccc1N1CCNCC1 Show InChI InChI=1S/C13H20N2/c1-2-5-12-6-3-4-7-13(12)15-10-8-14-9-11-15/h3-4,6-7,14H,2,5,8-11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical and Janssen Research Foundation Worldwide Curated by ChEMBL					Assay Description Binding affinity at rat Dopamine receptor D1 by [3H]-SCH-23,390 displacement.				J Med Chem 32: 1052-6 (1989) BindingDB Entry DOI: 10.7270/Q2HD7TNH
					More data for this Ligand-Target Pair