BDBM50017495 2-Benzo[b]thiophen-4-yl-N-[2-(3-hydroxymethyl-pyrrolidin-1-yl)-cyclohexyl]-N-methyl-acetamide; hydrochloride::CHEMBL541804

SMILES: CN([C@@H]1CCCC[C@H]1N1CCC(CO)C1)C(=O)Cc1cccc2sccc12

InChI Key: InChIKey=ZWCYXDPPXKYVFG-ODFWGIBRSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50017495   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50017495 (2-Benzo[b]thiophen-4-yl-N-[2-(3-hydroxymethyl-pyrr...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCC(CO)C1)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C22H30N2O2S/c1-23(22(26)13-17-5-4-8-21-18(17)10-12-27-21)19-6-2-3-7-20(19)24-11-9-16(14-24)15-25/h4-5,8,10,12,16,19-20,25H,2-3,6-7,9,11,13-15H2,1H3/t16?,19-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards opioid receptor kappa was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50017495 (2-Benzo[b]thiophen-4-yl-N-[2-(3-hydroxymethyl-pyrr...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCC(CO)C1)C(=O)Cc1cccc2sccc12 Show InChI InChI=1S/C22H30N2O2S/c1-23(22(26)13-17-5-4-8-21-18(17)10-12-27-21)19-6-2-3-7-20(19)24-11-9-16(14-24)15-25/h4-5,8,10,12,16,19-20,25H,2-3,6-7,9,11,13-15H2,1H3/t16?,19-,20-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Research Unit Curated by ChEMBL					Assay Description Binding affinity towards opioid receptor mu was determined				J Med Chem 32: 1620-6 (1989) BindingDB Entry DOI: 10.7270/Q2GH9JJB
					More data for this Ligand-Target Pair