BDBM50017514 8,11-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL300329
SMILES: COc1ccc(OC)c-2c1C[C@H]1N(C)CCc3cccc-2c13
InChI Key: InChIKey=DYMYTLRHYCZMTM-OAHLLOKOSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50017514 (8,11-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dib...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 8.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
College of Pharmacy University of Iowa Curated by ChEMBL | Assay Description Binding affinity of compound against 5-hydroxytryptamine 1A receptor binding site using radioligand [3H]8-OH-DPAT | J Med Chem 32: 1959-62 (1989) BindingDB Entry DOI: 10.7270/Q237799C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50017514 (8,11-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dib...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
College of Pharmacy University of Iowa Curated by ChEMBL | Assay Description Binding affinity of compound against Dopamine receptor D2 binding site using radioligand [3H]spiperone | J Med Chem 32: 1959-62 (1989) BindingDB Entry DOI: 10.7270/Q237799C | |||||||||||
More data for this Ligand-Target Pair |