BDBM50017593 CHEMBL3288625
SMILES: C[C@@H](NC(=S)NC[C@H](COC(=O)C(C)(C)C)Cc1ccc(C)c(C)c1)c1ccc(NS(C)(=O)=O)cc1
InChI Key: InChIKey=BVDOGTJSZAUADC-IFMALSPDSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vanilloid receptor (Rattus norvegicus (rat)) | BDBM50017593 (CHEMBL3288625) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced [45Ca2+] uptake by liquid scintill... | Bioorg Med Chem Lett 24: 2685-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.054 BindingDB Entry DOI: 10.7270/Q26111VT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vanilloid receptor (Rattus norvegicus (rat)) | BDBM50017593 (CHEMBL3288625) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description Displacement of [3H]RTX from rat TRPV1 after 60 mins by competitive binding assay | Bioorg Med Chem Lett 24: 2685-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.054 BindingDB Entry DOI: 10.7270/Q26111VT | |||||||||||
More data for this Ligand-Target Pair |