Found 3 hits for monomerid = 50017924 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Suppressor of tumorigenicity 14 protein
(Homo sapiens (Human)) | BDBM50017924
(CHEMBL3289044)Show SMILES NCCC(=O)Nc1ccc(Oc2cc(Oc3ccc(cc3)C(N)=N)cc(c2)C(=O)N[C@H]2CC[C@H](N)CC2)cc1 |r,wU:30.31,wD:33.35,(-.16,-9.38,;-.16,-7.84,;1.17,-7.07,;1.17,-5.53,;-.16,-4.76,;2.51,-4.76,;3.84,-5.53,;3.84,-7.07,;5.17,-7.84,;6.51,-7.07,;7.84,-7.84,;9.17,-7.07,;9.17,-5.53,;10.51,-4.76,;10.51,-3.22,;11.84,-2.45,;11.84,-.91,;13.18,-.14,;14.51,-.91,;14.51,-2.45,;13.18,-3.22,;15.84,-.14,;17.18,-.91,;15.84,1.4,;11.84,-5.53,;11.84,-7.07,;10.51,-7.84,;13.18,-7.84,;13.18,-9.38,;14.51,-7.07,;15.84,-7.84,;17.18,-7.07,;18.51,-7.84,;18.51,-9.38,;19.84,-10.15,;17.18,-10.15,;15.84,-9.38,;6.51,-5.53,;5.17,-4.76,)| Show InChI InChI=1S/C29H34N6O4/c30-14-13-27(36)34-21-7-11-24(12-8-21)39-26-16-19(29(37)35-22-5-3-20(31)4-6-22)15-25(17-26)38-23-9-1-18(2-10-23)28(32)33/h1-2,7-12,15-17,20,22H,3-6,13-14,30-31H2,(H3,32,33)(H,34,36)(H,35,37)/t20-,22- | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 116 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Aurigene Discovery Technologies Limited
Curated by ChEMBL
| Assay Description
Inhibition of recombinant matriptase (unknown origin) using Boc-Gln-Ala-Arg-7-amido-4-methyl coumarin hydrobromide |
Bioorg Med Chem 22: 3187-203 (2014)
Article DOI: 10.1016/j.bmc.2014.04.013
BindingDB Entry DOI: 10.7270/Q2J967ZD |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50017924
(CHEMBL3289044)Show SMILES NCCC(=O)Nc1ccc(Oc2cc(Oc3ccc(cc3)C(N)=N)cc(c2)C(=O)N[C@H]2CC[C@H](N)CC2)cc1 |r,wU:30.31,wD:33.35,(-.16,-9.38,;-.16,-7.84,;1.17,-7.07,;1.17,-5.53,;-.16,-4.76,;2.51,-4.76,;3.84,-5.53,;3.84,-7.07,;5.17,-7.84,;6.51,-7.07,;7.84,-7.84,;9.17,-7.07,;9.17,-5.53,;10.51,-4.76,;10.51,-3.22,;11.84,-2.45,;11.84,-.91,;13.18,-.14,;14.51,-.91,;14.51,-2.45,;13.18,-3.22,;15.84,-.14,;17.18,-.91,;15.84,1.4,;11.84,-5.53,;11.84,-7.07,;10.51,-7.84,;13.18,-7.84,;13.18,-9.38,;14.51,-7.07,;15.84,-7.84,;17.18,-7.07,;18.51,-7.84,;18.51,-9.38,;19.84,-10.15,;17.18,-10.15,;15.84,-9.38,;6.51,-5.53,;5.17,-4.76,)| Show InChI InChI=1S/C29H34N6O4/c30-14-13-27(36)34-21-7-11-24(12-8-21)39-26-16-19(29(37)35-22-5-3-20(31)4-6-22)15-25(17-26)38-23-9-1-18(2-10-23)28(32)33/h1-2,7-12,15-17,20,22H,3-6,13-14,30-31H2,(H3,32,33)(H,34,36)(H,35,37)/t20-,22- | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Aurigene Discovery Technologies Limited
Curated by ChEMBL
| Assay Description
Inhibition of human thrombin using Boc-Gln-Ala-Arg-7-amido-4-methyl coumarin hydrobromide |
Bioorg Med Chem 22: 3187-203 (2014)
Article DOI: 10.1016/j.bmc.2014.04.013
BindingDB Entry DOI: 10.7270/Q2J967ZD |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Bos taurus) | BDBM50017924
(CHEMBL3289044)Show SMILES NCCC(=O)Nc1ccc(Oc2cc(Oc3ccc(cc3)C(N)=N)cc(c2)C(=O)N[C@H]2CC[C@H](N)CC2)cc1 |r,wU:30.31,wD:33.35,(-.16,-9.38,;-.16,-7.84,;1.17,-7.07,;1.17,-5.53,;-.16,-4.76,;2.51,-4.76,;3.84,-5.53,;3.84,-7.07,;5.17,-7.84,;6.51,-7.07,;7.84,-7.84,;9.17,-7.07,;9.17,-5.53,;10.51,-4.76,;10.51,-3.22,;11.84,-2.45,;11.84,-.91,;13.18,-.14,;14.51,-.91,;14.51,-2.45,;13.18,-3.22,;15.84,-.14,;17.18,-.91,;15.84,1.4,;11.84,-5.53,;11.84,-7.07,;10.51,-7.84,;13.18,-7.84,;13.18,-9.38,;14.51,-7.07,;15.84,-7.84,;17.18,-7.07,;18.51,-7.84,;18.51,-9.38,;19.84,-10.15,;17.18,-10.15,;15.84,-9.38,;6.51,-5.53,;5.17,-4.76,)| Show InChI InChI=1S/C29H34N6O4/c30-14-13-27(36)34-21-7-11-24(12-8-21)39-26-16-19(29(37)35-22-5-3-20(31)4-6-22)15-25(17-26)38-23-9-1-18(2-10-23)28(32)33/h1-2,7-12,15-17,20,22H,3-6,13-14,30-31H2,(H3,32,33)(H,34,36)(H,35,37)/t20-,22- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Aurigene Discovery Technologies Limited
Curated by ChEMBL
| Assay Description
Inhibition of bovine plasma factor 10a using CH3OCO-D-CHA-Gly-Arg-pNA.AcoH substrate |
Bioorg Med Chem 22: 3187-203 (2014)
Article DOI: 10.1016/j.bmc.2014.04.013
BindingDB Entry DOI: 10.7270/Q2J967ZD |
More data for this
Ligand-Target Pair | |
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