BDBM50018028 CHEMBL3289949

SMILES: FC(F)(F)Oc1ccc(cc1)S(=O)(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12

InChI Key: InChIKey=PXFNUVRXAKDHRD-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50018028   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50018028 (CHEMBL3289949) Show SMILES FC(F)(F)Oc1ccc(cc1)S(=O)(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 Show InChI InChI=1S/C22H25F3N4O3S2/c23-22(24,25)32-17-7-9-18(10-8-17)34(30,31)26-11-3-4-12-28-13-15-29(16-14-28)21-19-5-1-2-6-20(19)33-27-21/h1-2,5-10,26H,3-4,11-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Adamed Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cell membrane after 60 mins by liquid scintillation countin...				J Med Chem 57: 4543-57 (2014) Article DOI: 10.1021/jm401895u BindingDB Entry DOI: 10.7270/Q2N29ZHX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50018028 (CHEMBL3289949) Show SMILES FC(F)(F)Oc1ccc(cc1)S(=O)(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 Show InChI InChI=1S/C22H25F3N4O3S2/c23-22(24,25)32-17-7-9-18(10-8-17)34(30,31)26-11-3-4-12-28-13-15-29(16-14-28)21-19-5-1-2-6-20(19)33-27-21/h1-2,5-10,26H,3-4,11-16H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Adamed Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5-HT7 receptor expressed in CHO-K1 cell membrane after 120 mins by liquid scintillation counting analy...				J Med Chem 57: 4543-57 (2014) Article DOI: 10.1021/jm401895u BindingDB Entry DOI: 10.7270/Q2N29ZHX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50018028 (CHEMBL3289949) Show SMILES FC(F)(F)Oc1ccc(cc1)S(=O)(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 Show InChI InChI=1S/C22H25F3N4O3S2/c23-22(24,25)32-17-7-9-18(10-8-17)34(30,31)26-11-3-4-12-28-13-15-29(16-14-28)21-19-5-1-2-6-20(19)33-27-21/h1-2,5-10,26H,3-4,11-16H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Adamed Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]LSDm from human recombinant 5-HT6 receptor expressed in HEK293 cell membrane after 60 mins by liquid scintillation counting analy...				J Med Chem 57: 4543-57 (2014) Article DOI: 10.1021/jm401895u BindingDB Entry DOI: 10.7270/Q2N29ZHX
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50018028 (CHEMBL3289949) Show SMILES FC(F)(F)Oc1ccc(cc1)S(=O)(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 Show InChI InChI=1S/C22H25F3N4O3S2/c23-22(24,25)32-17-7-9-18(10-8-17)34(30,31)26-11-3-4-12-28-13-15-29(16-14-28)21-19-5-1-2-6-20(19)33-27-21/h1-2,5-10,26H,3-4,11-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Adamed Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human recombinant D2 receptor expressed in CHO-K1 cell membrane after 60 mins by liquid scintillation coun...				J Med Chem 57: 4543-57 (2014) Article DOI: 10.1021/jm401895u BindingDB Entry DOI: 10.7270/Q2N29ZHX
					More data for this Ligand-Target Pair