BDBM50018212 3-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-propionic acid::CHEMBL440104

SMILES: ONC(=O)CC(Cc1ccccc1)C(=O)NCCC(O)=O

InChI Key: InChIKey=CMHAGDRBKHHGLD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50018212   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aminopeptidase N (Sus scrofa (Pig))	BDBM50018212 (3-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...) Show SMILES ONC(=O)CC(Cc1ccccc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C14H18N2O5/c17-12(16-21)9-11(8-10-4-2-1-3-5-10)14(20)15-7-6-13(18)19/h1-5,11,21H,6-9H2,(H,15,20)(H,16,17)(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of Aminopeptidase N activity in pig kidney with 10 nM [3H]-Leu-enkephalin as substrate				J Med Chem 32: 1497-503 (1989) BindingDB Entry DOI: 10.7270/Q2610Z9F
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50018212 (3-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...) Show SMILES ONC(=O)CC(Cc1ccccc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C14H18N2O5/c17-12(16-21)9-11(8-10-4-2-1-3-5-10)14(20)15-7-6-13(18)19/h1-5,11,21H,6-9H2,(H,15,20)(H,16,17)(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of neutral endopeptidase activity in rabbit kidney with 20 nM [3H]-D-Ala2-Leu-enkephalin as substrate				J Med Chem 32: 1497-503 (1989) BindingDB Entry DOI: 10.7270/Q2610Z9F
					More data for this Ligand-Target Pair