BDBM50018223 CHEMBL3290001

SMILES: Fc1ccc2c(noc2c1)C1CCN(CCNS(=O)(=O)c2cccc3ccccc23)CC1

InChI Key: InChIKey=ZHUCAIBXMOFDCR-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50018223   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50018223 (CHEMBL3290001) Show SMILES Fc1ccc2c(noc2c1)C1CCN(CCNS(=O)(=O)c2cccc3ccccc23)CC1 Show InChI InChI=1S/C24H24FN3O3S/c25-19-8-9-21-22(16-19)31-27-24(21)18-10-13-28(14-11-18)15-12-26-32(29,30)23-7-3-5-17-4-1-2-6-20(17)23/h1-9,16,18,26H,10-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Adamed Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cell membrane after 60 mins by liquid scintillation countin...				J Med Chem 57: 4543-57 (2014) Article DOI: 10.1021/jm401895u BindingDB Entry DOI: 10.7270/Q2N29ZHX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50018223 (CHEMBL3290001) Show SMILES Fc1ccc2c(noc2c1)C1CCN(CCNS(=O)(=O)c2cccc3ccccc23)CC1 Show InChI InChI=1S/C24H24FN3O3S/c25-19-8-9-21-22(16-19)31-27-24(21)18-10-13-28(14-11-18)15-12-26-32(29,30)23-7-3-5-17-4-1-2-6-20(17)23/h1-9,16,18,26H,10-15H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Adamed Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5-HT7 receptor expressed in CHO-K1 cell membrane after 120 mins by liquid scintillation counting analy...				J Med Chem 57: 4543-57 (2014) Article DOI: 10.1021/jm401895u BindingDB Entry DOI: 10.7270/Q2N29ZHX
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50018223 (CHEMBL3290001) Show SMILES Fc1ccc2c(noc2c1)C1CCN(CCNS(=O)(=O)c2cccc3ccccc23)CC1 Show InChI InChI=1S/C24H24FN3O3S/c25-19-8-9-21-22(16-19)31-27-24(21)18-10-13-28(14-11-18)15-12-26-32(29,30)23-7-3-5-17-4-1-2-6-20(17)23/h1-9,16,18,26H,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Adamed Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human recombinant D2 receptor expressed in CHO-K1 cell membrane after 60 mins by liquid scintillation coun...				J Med Chem 57: 4543-57 (2014) Article DOI: 10.1021/jm401895u BindingDB Entry DOI: 10.7270/Q2N29ZHX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50018223 (CHEMBL3290001) Show SMILES Fc1ccc2c(noc2c1)C1CCN(CCNS(=O)(=O)c2cccc3ccccc23)CC1 Show InChI InChI=1S/C24H24FN3O3S/c25-19-8-9-21-22(16-19)31-27-24(21)18-10-13-28(14-11-18)15-12-26-32(29,30)23-7-3-5-17-4-1-2-6-20(17)23/h1-9,16,18,26H,10-15H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Adamed Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]LSDm from human recombinant 5-HT6 receptor expressed in HEK293 cell membrane after 60 mins by liquid scintillation counting analy...				J Med Chem 57: 4543-57 (2014) Article DOI: 10.1021/jm401895u BindingDB Entry DOI: 10.7270/Q2N29ZHX
					More data for this Ligand-Target Pair