null

SMILES: Fc1ccc2c(noc2c1)C1CCN(CCCCNS(=O)(=O)c2cccc3scnc23)CC1

InChI Key: InChIKey=ZLGZCZCALIKICJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50018255   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50018255 (CHEMBL3290021) Show SMILES Fc1ccc2c(noc2c1)C1CCN(CCCCNS(=O)(=O)c2cccc3scnc23)CC1 Show InChI InChI=1S/C23H25FN4O3S2/c24-17-6-7-18-19(14-17)31-27-22(18)16-8-12-28(13-9-16)11-2-1-10-26-33(29,30)21-5-3-4-20-23(21)25-15-32-20/h3-7,14-16,26H,1-2,8-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Adamed Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cell membrane after 60 mins by liquid scintillation countin...				J Med Chem 57: 4543-57 (2014) Article DOI: 10.1021/jm401895u BindingDB Entry DOI: 10.7270/Q2N29ZHX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50018255 (CHEMBL3290021) Show SMILES Fc1ccc2c(noc2c1)C1CCN(CCCCNS(=O)(=O)c2cccc3scnc23)CC1 Show InChI InChI=1S/C23H25FN4O3S2/c24-17-6-7-18-19(14-17)31-27-22(18)16-8-12-28(13-9-16)11-2-1-10-26-33(29,30)21-5-3-4-20-23(21)25-15-32-20/h3-7,14-16,26H,1-2,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Adamed Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5-HT7 receptor expressed in CHO-K1 cell membrane after 120 mins by liquid scintillation counting analy...				J Med Chem 57: 4543-57 (2014) Article DOI: 10.1021/jm401895u BindingDB Entry DOI: 10.7270/Q2N29ZHX
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50018255 (CHEMBL3290021) Show SMILES Fc1ccc2c(noc2c1)C1CCN(CCCCNS(=O)(=O)c2cccc3scnc23)CC1 Show InChI InChI=1S/C23H25FN4O3S2/c24-17-6-7-18-19(14-17)31-27-22(18)16-8-12-28(13-9-16)11-2-1-10-26-33(29,30)21-5-3-4-20-23(21)25-15-32-20/h3-7,14-16,26H,1-2,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Adamed Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human recombinant D2 receptor expressed in CHO-K1 cell membrane after 60 mins by liquid scintillation coun...				J Med Chem 57: 4543-57 (2014) Article DOI: 10.1021/jm401895u BindingDB Entry DOI: 10.7270/Q2N29ZHX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50018255 (CHEMBL3290021) Show SMILES Fc1ccc2c(noc2c1)C1CCN(CCCCNS(=O)(=O)c2cccc3scnc23)CC1 Show InChI InChI=1S/C23H25FN4O3S2/c24-17-6-7-18-19(14-17)31-27-22(18)16-8-12-28(13-9-16)11-2-1-10-26-33(29,30)21-5-3-4-20-23(21)25-15-32-20/h3-7,14-16,26H,1-2,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Adamed Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]LSDm from human recombinant 5-HT6 receptor expressed in HEK293 cell membrane after 60 mins by liquid scintillation counting analy...				J Med Chem 57: 4543-57 (2014) Article DOI: 10.1021/jm401895u BindingDB Entry DOI: 10.7270/Q2N29ZHX
					More data for this Ligand-Target Pair