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SMILES: O=C(CN1CCCCC1CN1CCCC1)N1c2ccccc2C(=O)Nc2cccnc12

InChI Key: InChIKey=IKTJYOBPKIOLOH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50018310   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (RAT)	BDBM50018310 (11-[2-(2-Pyrrolidin-1-ylmethyl-piperidin-1-yl)-ace...) Show SMILES O=C(CN1CCCCC1CN1CCCC1)N1c2ccccc2C(=O)Nc2cccnc12 Show InChI InChI=1S/C24H29N5O2/c30-22(17-28-15-4-3-8-18(28)16-27-13-5-6-14-27)29-21-11-2-1-9-19(21)24(31)26-20-10-7-12-25-23(20)29/h1-2,7,9-12,18H,3-6,8,13-17H2,(H,26,31)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Karl Thomae GmbH Curated by ChEMBL					Assay Description Binding affinity for glandular muscarinic acetylcholine receptor M3 in rat assayed using 0.3 nM [3H]-N-methylscopolamine as radioligand				J Med Chem 32: 1718-24 (1989) BindingDB Entry DOI: 10.7270/Q2XG9Q4Q
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (RAT)	BDBM50018310 (11-[2-(2-Pyrrolidin-1-ylmethyl-piperidin-1-yl)-ace...) Show SMILES O=C(CN1CCCCC1CN1CCCC1)N1c2ccccc2C(=O)Nc2cccnc12 Show InChI InChI=1S/C24H29N5O2/c30-22(17-28-15-4-3-8-18(28)16-27-13-5-6-14-27)29-21-11-2-1-9-19(21)24(31)26-20-10-7-12-25-23(20)29/h1-2,7,9-12,18H,3-6,8,13-17H2,(H,26,31)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
College of Pharmacy Curated by ChEMBL					Assay Description Inhibition of rat submandibular muscarinic (M3) receptor isolated from tissue homogenates				J Med Chem 37: 3775-88 (1994) BindingDB Entry DOI: 10.7270/Q2QC02JX
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50018310 (11-[2-(2-Pyrrolidin-1-ylmethyl-piperidin-1-yl)-ace...) Show SMILES O=C(CN1CCCCC1CN1CCCC1)N1c2ccccc2C(=O)Nc2cccnc12 Show InChI InChI=1S/C24H29N5O2/c30-22(17-28-15-4-3-8-18(28)16-27-13-5-6-14-27)29-21-11-2-1-9-19(21)24(31)26-20-10-7-12-25-23(20)29/h1-2,7,9-12,18H,3-6,8,13-17H2,(H,26,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
College of Pharmacy Curated by ChEMBL					Assay Description Inhibition of muscarinic (M2) receptor isolated from rat atria				J Med Chem 37: 3775-88 (1994) BindingDB Entry DOI: 10.7270/Q2QC02JX
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50018310 (11-[2-(2-Pyrrolidin-1-ylmethyl-piperidin-1-yl)-ace...) Show SMILES O=C(CN1CCCCC1CN1CCCC1)N1c2ccccc2C(=O)Nc2cccnc12 Show InChI InChI=1S/C24H29N5O2/c30-22(17-28-15-4-3-8-18(28)16-27-13-5-6-14-27)29-21-11-2-1-9-19(21)24(31)26-20-10-7-12-25-23(20)29/h1-2,7,9-12,18H,3-6,8,13-17H2,(H,26,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Karl Thomae GmbH Curated by ChEMBL					Assay Description Binding affinity to the rat cardiac muscarinic acetylcholine receptor M2 using 0.3 nM [3H]-N-methylscopolamine as radioligand				J Med Chem 32: 1718-24 (1989) BindingDB Entry DOI: 10.7270/Q2XG9Q4Q
					More data for this Ligand-Target Pair