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BDBM50018316 2-Butyl-3',4'-dimethoxy-biphenyl-4-carboxylic acid (1-methyl-4-pyridin-3-yl-butyl)-amide::CHEMBL51692

SMILES: CCCCc1cc(ccc1-c1ccc(OC)c(OC)c1)C(=O)N[C@H](C)CCCc1cccnc1

InChI Key: InChIKey=CVYKZBQKPODZOD-OAQYLSRUSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50018316   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018316
PNG
(2-Butyl-3',4'-dimethoxy-biphenyl-4-carboxylic acid...)
Show SMILES CCCCc1cc(ccc1-c1ccc(OC)c(OC)c1)C(=O)N[C@H](C)CCCc1cccnc1
Show InChI InChI=1S/C29H36N2O3/c1-5-6-12-23-18-25(13-15-26(23)24-14-16-27(33-3)28(19-24)34-4)29(32)31-21(2)9-7-10-22-11-8-17-30-20-22/h8,11,13-21H,5-7,9-10,12H2,1-4H3,(H,31,32)/t21-/m1/s1
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n/an/a 4n/an/an/an/an/an/a



Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand.


J Med Chem 32: 1814-20 (1989)


BindingDB Entry DOI: 10.7270/Q2SQ8ZCJ
More data for this
Ligand-Target Pair