BDBM50018369 5,5-Bis-(4-methoxy-phenyl)-penta-2,4-dienoic acid (1-methyl-4-pyridin-3-yl-butyl)-amide::CHEMBL50244

SMILES: [#6]-[#8]-c1ccc(cc1)-[#6](=[#6]\[#6]=[#6]\[#6](=O)-[#7]-[#6@@H](-[#6])-[#6]-[#6]-[#6]-c1cccnc1)\c1ccc(-[#8]-[#6])cc1

InChI Key: InChIKey=PSJXTUCCJLEFFC-PXWJQCMDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50018369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50018369 (5,5-Bis-(4-methoxy-phenyl)-penta-2,4-dienoic acid ...) Show SMILES [#6]-[#8]-c1ccc(cc1)-[#6](=[#6]\[#6]=[#6]\[#6](=O)-[#7]-[#6@@H](-[#6])-[#6]-[#6]-[#6]-c1cccnc1)\c1ccc(-[#8]-[#6])cc1 Show InChI InChI=1S/C29H32N2O3/c1-22(7-4-8-23-9-6-20-30-21-23)31-29(32)11-5-10-28(24-12-16-26(33-2)17-13-24)25-14-18-27(34-3)19-15-25/h5-6,9-22H,4,7-8H2,1-3H3,(H,31,32)/b11-5+/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Roche Research Center Curated by ChEMBL					Assay Description Inhibition of [3H]-PAF binding to dog platelets.				J Med Chem 32: 1820-35 (1989) BindingDB Entry DOI: 10.7270/Q2NZ86MR
					More data for this Ligand-Target Pair