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BDBM50018451 2-{4-[3-(Naphthalen-1-yloxy)-propylamino]-butyl}-isoindole-1,3-dione::CHEMBL56148

SMILES: O=C1N(CCCCNCCCOc2cccc3ccccc23)C(=O)c2ccccc12

InChI Key: InChIKey=IVAOZEOEFNHRMH-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50018451   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50018451
PNG
(2-{4-[3-(Naphthalen-1-yloxy)-propylamino]-butyl}-i...)
Show SMILES O=C1N(CCCCNCCCOc2cccc3ccccc23)C(=O)c2ccccc12
Show InChI InChI=1S/C25H26N2O3/c28-24-21-12-3-4-13-22(21)25(29)27(24)17-6-5-15-26-16-8-18-30-23-14-7-10-19-9-1-2-11-20(19)23/h1-4,7,9-14,26H,5-6,8,15-18H2
PDB

KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 25n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]-OH-DPAT displacement.

J Med Chem 32: 1921-6 (1989)


BindingDB Entry DOI: 10.7270/Q2J67FWB
More data for this
Ligand-Target Pair