BDBM50018468 2-{3-[3-(Naphthalen-1-yloxy)-propylamino]-propyl}-isoindole-1,3-dione::CHEMBL57214

SMILES: O=C1N(CCCNCCCOc2cccc3ccccc23)C(=O)c2ccccc12

InChI Key: InChIKey=JYFNJQRJSURLDT-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50018468   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50018468 (2-{3-[3-(Naphthalen-1-yloxy)-propylamino]-propyl}-...) Show SMILES O=C1N(CCCNCCCOc2cccc3ccccc23)C(=O)c2ccccc12 Show InChI InChI=1S/C24H24N2O3/c27-23-20-11-3-4-12-21(20)24(28)26(23)16-6-14-25-15-7-17-29-22-13-5-9-18-8-1-2-10-19(18)22/h1-5,8-13,25H,6-7,14-17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity of compound towards 5-HT 1A receptor by measuring ability to displace [3H]-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat stria...				J Med Chem 32: 1921-6 (1989) BindingDB Entry DOI: 10.7270/Q2J67FWB
					More data for this Ligand-Target Pair