BDBM50018551 (+/-)-1'-(4-fluorobenzyl)-3-phenyl-3,4'-bipiperidine-2,6-dione::1'-(4-Fluoro-benzyl)-3-phenyl-[3,4']bipiperidinyl-2,6-dione::CHEMBL274817

SMILES: Fc1ccc(CN2CCC(CC2)C2(CCC(=O)NC2=O)c2ccccc2)cc1

InChI Key: InChIKey=VTMACVBTDNAUST-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50018551   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor (RAT)	BDBM50018551 ((+/-)-1'-(4-fluorobenzyl)-3-phenyl-3,4'-bipiperidi...) Show SMILES Fc1ccc(CN2CCC(CC2)C2(CCC(=O)NC2=O)c2ccccc2)cc1 Show InChI InChI=1S/C23H25FN2O2/c24-20-8-6-17(7-9-20)16-26-14-11-19(12-15-26)23(18-4-2-1-3-5-18)13-10-21(27)25-22(23)28/h1-9,19H,10-16H2,(H,25,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Johns Hopkins Medical Institutions Curated by ChEMBL					Assay Description Displacement of [3H]N-methylscopolamine from rat brain homogenate				J Med Chem 32: 1057-62 (1989) BindingDB Entry DOI: 10.7270/Q29S1T87
					More data for this Ligand-Target Pair
chemokine (C-X-C motif) receptor 3 (Homo sapiens (Human))	BDBM50018551 ((+/-)-1'-(4-fluorobenzyl)-3-phenyl-3,4'-bipiperidi...) Show SMILES Fc1ccc(CN2CCC(CC2)C2(CCC(=O)NC2=O)c2ccccc2)cc1 Show InChI InChI=1S/C23H25FN2O2/c24-20-8-6-17(7-9-20)16-26-14-11-19(12-15-26)23(18-4-2-1-3-5-18)13-10-21(27)25-22(23)28/h1-9,19H,10-16H2,(H,25,27,28)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson PRD Curated by ChEMBL					Assay Description Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...				Bioorg Med Chem Lett 18: 5819-23 (2009) Article DOI: 10.1016/j.bmcl.2008.07.115 BindingDB Entry DOI: 10.7270/Q2RV0NQB
					More data for this Ligand-Target Pair