Found 6 hits for monomerid = 50018625 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50018625
(CHEMBL3291001)Show SMILES OP(O)(=O)C(NS(=O)(=O)c1ccc(Cl)cc1)P(O)(O)=O Show InChI InChI=1S/C7H10ClNO8P2S/c8-5-1-3-6(4-2-5)20(16,17)9-7(18(10,11)12)19(13,14)15/h1-4,7,9H,(H2,10,11,12)(H2,13,14,15) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 1 pretreated for 15 mins by stopped flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 2617-20 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.077 BindingDB Entry DOI: 10.7270/Q2GB25KV |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50018625
(CHEMBL3291001)Show SMILES OP(O)(=O)C(NS(=O)(=O)c1ccc(Cl)cc1)P(O)(O)=O Show InChI InChI=1S/C7H10ClNO8P2S/c8-5-1-3-6(4-2-5)20(16,17)9-7(18(10,11)12)19(13,14)15/h1-4,7,9H,(H2,10,11,12)(H2,13,14,15) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 2 pretreated for 15 mins by stopped flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 2617-20 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.077 BindingDB Entry DOI: 10.7270/Q2GB25KV |
More data for this Ligand-Target Pair | |
Carbonic Anhydrase XIV
(Homo sapiens (Human)) | BDBM50018625
(CHEMBL3291001)Show SMILES OP(O)(=O)C(NS(=O)(=O)c1ccc(Cl)cc1)P(O)(O)=O Show InChI InChI=1S/C7H10ClNO8P2S/c8-5-1-3-6(4-2-5)20(16,17)9-7(18(10,11)12)19(13,14)15/h1-4,7,9H,(H2,10,11,12)(H2,13,14,15) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 14 pretreated for 15 mins by stopped flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 2617-20 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.077 BindingDB Entry DOI: 10.7270/Q2GB25KV |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50018625
(CHEMBL3291001)Show SMILES OP(O)(=O)C(NS(=O)(=O)c1ccc(Cl)cc1)P(O)(O)=O Show InChI InChI=1S/C7H10ClNO8P2S/c8-5-1-3-6(4-2-5)20(16,17)9-7(18(10,11)12)19(13,14)15/h1-4,7,9H,(H2,10,11,12)(H2,13,14,15) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibition of human recombinant MMP-2 pretreated for 30 mins measured 2 to 4 hrs after Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition by fluo... |
Bioorg Med Chem Lett 24: 2617-20 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.077 BindingDB Entry DOI: 10.7270/Q2GB25KV |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50018625
(CHEMBL3291001)Show SMILES OP(O)(=O)C(NS(=O)(=O)c1ccc(Cl)cc1)P(O)(O)=O Show InChI InChI=1S/C7H10ClNO8P2S/c8-5-1-3-6(4-2-5)20(16,17)9-7(18(10,11)12)19(13,14)15/h1-4,7,9H,(H2,10,11,12)(H2,13,14,15) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 464 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 12 pretreated for 15 mins by stopped flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 2617-20 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.077 BindingDB Entry DOI: 10.7270/Q2GB25KV |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50018625
(CHEMBL3291001)Show SMILES OP(O)(=O)C(NS(=O)(=O)c1ccc(Cl)cc1)P(O)(O)=O Show InChI InChI=1S/C7H10ClNO8P2S/c8-5-1-3-6(4-2-5)20(16,17)9-7(18(10,11)12)19(13,14)15/h1-4,7,9H,(H2,10,11,12)(H2,13,14,15) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 95 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 9 pretreated for 15 mins by stopped flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 2617-20 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.077 BindingDB Entry DOI: 10.7270/Q2GB25KV |
More data for this Ligand-Target Pair | |