BDBM50018814 CHEMBL3291352

SMILES: [H][C@@]12CC[C@@](C)(c3nn(c(OC)c13)-c1ccc(C)cc1)C2(C)C

InChI Key: InChIKey=LLZZIUXEXKHAHP-KUHUBIRLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50018814   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50018814 (CHEMBL3291352) Show SMILES [H][C@@]12CC[C@@](C)(c3nn(c(OC)c13)-c1ccc(C)cc1)C2(C)C |r| Show InChI InChI=1S/C19H24N2O/c1-12-6-8-13(9-7-12)21-17(22-5)15-14-10-11-19(4,16(15)20-21)18(14,2)3/h6-9,14H,10-11H2,1-5H3/t14-,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISA				Bioorg Med Chem Lett 24: 2707-11 (2014) Article DOI: 10.1016/j.bmcl.2014.04.049 BindingDB Entry DOI: 10.7270/Q2TM7CPF
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Rattus norvegicus (rat))	BDBM50018814 (CHEMBL3291352) Show SMILES [H][C@@]12CC[C@@](C)(c3nn(c(OC)c13)-c1ccc(C)cc1)C2(C)C |r| Show InChI InChI=1S/C19H24N2O/c1-12-6-8-13(9-7-12)21-17(22-5)15-14-10-11-19(4,16(15)20-21)18(14,2)3/h6-9,14H,10-11H2,1-5H3/t14-,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISA				Bioorg Med Chem Lett 24: 2707-11 (2014) Article DOI: 10.1016/j.bmcl.2014.04.049 BindingDB Entry DOI: 10.7270/Q2TM7CPF
					More data for this Ligand-Target Pair