null

SMILES: NS(=O)(=O)c1cc(-c2nnc(o2)-c2ccc(Cl)cc2)c(Cl)cc1Cl

InChI Key: InChIKey=NFESGNOLEXZHKX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50019584   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50019584 (CHEMBL3291093) Show SMILES NS(=O)(=O)c1cc(-c2nnc(o2)-c2ccc(Cl)cc2)c(Cl)cc1Cl Show InChI InChI=1S/C14H8Cl3N3O3S/c15-8-3-1-7(2-4-8)13-19-20-14(23-13)9-5-12(24(18,21)22)11(17)6-10(9)16/h1-6H,(H2,18,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned transmembrane tumor-associated catalytic domain of carbonic anhydrase 9 preincubated for 15 mins by stopped flow CO2 hydra...				Eur J Med Chem 82: 47-55 (2014) Article DOI: 10.1016/j.ejmech.2014.05.039 BindingDB Entry DOI: 10.7270/Q2X63PH6
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50019584 (CHEMBL3291093) Show SMILES NS(=O)(=O)c1cc(-c2nnc(o2)-c2ccc(Cl)cc2)c(Cl)cc1Cl Show InChI InChI=1S/C14H8Cl3N3O3S/c15-8-3-1-7(2-4-8)13-19-20-14(23-13)9-5-12(24(18,21)22)11(17)6-10(9)16/h1-6H,(H2,18,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned transmembrane tumor-associated catalytic domain of carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydr...				Eur J Med Chem 82: 47-55 (2014) Article DOI: 10.1016/j.ejmech.2014.05.039 BindingDB Entry DOI: 10.7270/Q2X63PH6
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50019584 (CHEMBL3291093) Show SMILES NS(=O)(=O)c1cc(-c2nnc(o2)-c2ccc(Cl)cc2)c(Cl)cc1Cl Show InChI InChI=1S/C14H8Cl3N3O3S/c15-8-3-1-7(2-4-8)13-19-20-14(23-13)9-5-12(24(18,21)22)11(17)6-10(9)16/h1-6H,(H2,18,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay				Eur J Med Chem 82: 47-55 (2014) Article DOI: 10.1016/j.ejmech.2014.05.039 BindingDB Entry DOI: 10.7270/Q2X63PH6
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50019584 (CHEMBL3291093) Show SMILES NS(=O)(=O)c1cc(-c2nnc(o2)-c2ccc(Cl)cc2)c(Cl)cc1Cl Show InChI InChI=1S/C14H8Cl3N3O3S/c15-8-3-1-7(2-4-8)13-19-20-14(23-13)9-5-12(24(18,21)22)11(17)6-10(9)16/h1-6H,(H2,18,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	671	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay				Eur J Med Chem 82: 47-55 (2014) Article DOI: 10.1016/j.ejmech.2014.05.039 BindingDB Entry DOI: 10.7270/Q2X63PH6
					More data for this Ligand-Target Pair