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SMILES: CCOCCn1c(nc2ccccc12)N1CCCN(Cc2ccccc2)CC1

InChI Key: InChIKey=DFLPFGZIQLILOG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50019625   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))		BDBM50019625
PNG
(2-(4-Benzyl-[1,4]diazepan-1-yl)-1-(2-ethoxy-ethyl)...)
Show SMILES CCOCCn1c(nc2ccccc12)N1CCCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C23H30N4O/c1-2-28-18-17-27-22-12-7-6-11-21(22)24-23(27)26-14-8-13-25(15-16-26)19-20-9-4-3-5-10-20/h3-7,9-12H,2,8,13-19H2,1H3
UniProtKB/SwissProt

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PC sid
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Similars
PubMed
n/an/a 15n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of histamine-induced contractions in guinea pig ileum

J Med Chem 29: 1178-83 (1987)


BindingDB Entry DOI: 10.7270/Q2QR4XPC
More data for this
Ligand-Target Pair