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SMILES: CCOCCn1c(nc2ccccc12)N1CCN(Cc2ccccc2)CC1

InChI Key: InChIKey=GEDWDORUFBMJEJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50019627   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))		BDBM50019627
PNG
(2-(4-Benzyl-piperazin-1-yl)-1-(2-ethoxy-ethyl)-1H-...)
Show SMILES CCOCCn1c(nc2ccccc12)N1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C22H28N4O/c1-2-27-17-16-26-21-11-7-6-10-20(21)23-22(26)25-14-12-24(13-15-25)18-19-8-4-3-5-9-19/h3-11H,2,12-18H2,1H3
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PubMed
n/an/a 27n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of histamine-induced contractions in guinea pig ileum

J Med Chem 29: 1178-83 (1987)


BindingDB Entry DOI: 10.7270/Q2QR4XPC
More data for this
Ligand-Target Pair