BDBM50019711 CHEMBL3286585
SMILES: Fc1cccc(c1)S(=O)(=O)n1cc2CC3CNCCN3c3cccc1c23
InChI Key: InChIKey=FRDVOZMDNOYFJK-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50019711 (CHEMBL3286585) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in hamster BHK cells after 60 mins by scintillation counting analysis | J Med Chem 57: 5823-8 (2014) Article DOI: 10.1021/jm5003759 BindingDB Entry DOI: 10.7270/Q2D79D04 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50019711 (CHEMBL3286585) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine from human 5-HT2C receptor expressed in human tsA201 cells after 1 hr by scintillation counting analysis | J Med Chem 57: 5823-8 (2014) Article DOI: 10.1021/jm5003759 BindingDB Entry DOI: 10.7270/Q2D79D04 | |||||||||||
More data for this Ligand-Target Pair |