null

SMILES: [H][C@]12CS[C@@H](CCCCC(=O)NCCCOCCOCCOCCCNC(=O)CC(COc3ccc(cc3)-c3nc4ccccc4n3Cc3ccccc3)n3c(nc4ccccc34)-c3ccccc3)[C@@]1([H])NC(=O)N2

InChI Key: InChIKey=YFCRJRYCPJUAQH-XAZUWAHXSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50019796   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019796 (CHEMBL3286888) Show SMILES [H][C@]12CS[C@@H](CCCCC(=O)NCCCOCCOCCOCCCNC(=O)CC(COc3ccc(cc3)-c3nc4ccccc4n3Cc3ccccc3)n3c(nc4ccccc34)-c3ccccc3)[C@@]1([H])NC(=O)N2 |r| Show InChI InChI=1S/C57H66N8O7S/c66-52(24-12-11-23-51-54-48(40-73-51)62-57(68)63-54)58-29-13-31-69-33-35-71-36-34-70-32-14-30-59-53(67)37-44(65-50-22-10-8-20-47(50)61-56(65)42-17-5-2-6-18-42)39-72-45-27-25-43(26-28-45)55-60-46-19-7-9-21-49(46)64(55)38-41-15-3-1-4-16-41/h1-10,15-22,25-28,44,48,51,54H,11-14,23-24,29-40H2,(H,58,66)(H,59,67)(H2,62,63,68)/t44?,48-,51-,54-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	328	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair