BDBM50019809 CHEMBL3286895

SMILES: Cc1cccc(Cn2c(nc3ccccc23)-c2ccc(OCC(C3CCNCC3)n3c(nc4ccccc34)-c3ccccc3)cc2)c1

InChI Key: InChIKey=BIGUAKCWPJNGCV-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50019809   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019809 (CHEMBL3286895) Show SMILES Cc1cccc(Cn2c(nc3ccccc23)-c2ccc(OCC(C3CCNCC3)n3c(nc4ccccc34)-c3ccccc3)cc2)c1 Show InChI InChI=1S/C41H39N5O/c1-29-10-9-11-30(26-29)27-45-37-16-7-5-14-35(37)43-40(45)33-18-20-34(21-19-33)47-28-39(31-22-24-42-25-23-31)46-38-17-8-6-15-36(38)44-41(46)32-12-3-2-4-13-32/h2-21,26,31,39,42H,22-25,27-28H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	191	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair