BDBM50019815 CHEMBL3286899

SMILES: CC(C)C(COC(=O)C1CCN(CC1)c1nc2ccccc2n1Cc1ccccc1)n1c(nc2ccccc12)-c1ccccc1

InChI Key: InChIKey=LZRNGISDTHAYNF-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50019815   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019815 (CHEMBL3286899) Show SMILES CC(C)C(COC(=O)C1CCN(CC1)c1nc2ccccc2n1Cc1ccccc1)n1c(nc2ccccc12)-c1ccccc1 Show InChI InChI=1S/C38H39N5O2/c1-27(2)35(43-34-20-12-10-18-32(34)39-36(43)29-15-7-4-8-16-29)26-45-37(44)30-21-23-41(24-22-30)38-40-31-17-9-11-19-33(31)42(38)25-28-13-5-3-6-14-28/h3-20,27,30,35H,21-26H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair