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BDBM50019826 CHEMBL3286906

SMILES: O=C(OCC(CC1CCNCC1)n1c(nc2ccccc12)-c1ccccc1)C1CCN(CC1)c1nc2ccccc2n1Cc1ccccc1

InChI Key: InChIKey=ZFHBIFNRZSIJML-UHFFFAOYSA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50019826   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta


(Homo sapiens (Human))		BDBM50019826
PNG
(CHEMBL3286906)
Show SMILES O=C(OCC(CC1CCNCC1)n1c(nc2ccccc12)-c1ccccc1)C1CCN(CC1)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C41H44N6O2/c48-40(33-21-25-45(26-22-33)41-44-35-15-7-9-17-37(35)46(41)28-31-11-3-1-4-12-31)49-29-34(27-30-19-23-42-24-20-30)47-38-18-10-8-16-36(38)43-39(47)32-13-5-2-6-14-32/h1-18,30,33-34,42H,19-29H2
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/a 14n/an/an/an/an/a



Max Planck Institute of Molecular Physiology

Curated by ChEMBL


Assay Description
Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay

J Med Chem 57: 5435-48 (2014)


Article DOI: 10.1021/jm500632s
BindingDB Entry DOI: 10.7270/Q24Q7WJP
More data for this
Ligand-Target Pair