BDBM50019863 CHEMBL3286927

SMILES: CC(C)c1c(cc(-c2ccccc2)n1CCCn1ccnc1C)-c1nc2ccccc2n1CC1CCCC1

InChI Key: InChIKey=WXDAPKXJPLCTGT-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50019863   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019863 (CHEMBL3286927) Show SMILES CC(C)c1c(cc(-c2ccccc2)n1CCCn1ccnc1C)-c1nc2ccccc2n1CC1CCCC1 Show InChI InChI=1S/C33H39N5/c1-24(2)32-28(33-35-29-16-9-10-17-30(29)38(33)23-26-12-7-8-13-26)22-31(27-14-5-4-6-15-27)37(32)20-11-19-36-21-18-34-25(36)3/h4-6,9-10,14-18,21-22,24,26H,7-8,11-13,19-20,23H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	347	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair