BDBM50019864 CHEMBL3286928

SMILES: CC(C)c1c(cc(-c2ccccc2)n1CCCn1ccnc1C)-c1nc2ccccc2n1Cc1ccccc1

InChI Key: InChIKey=UDHNPYZXHSINNV-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50019864   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019864 (CHEMBL3286928) Show SMILES CC(C)c1c(cc(-c2ccccc2)n1CCCn1ccnc1C)-c1nc2ccccc2n1Cc1ccccc1 Show InChI InChI=1S/C34H35N5/c1-25(2)33-29(34-36-30-17-10-11-18-31(30)39(34)24-27-13-6-4-7-14-27)23-32(28-15-8-5-9-16-28)38(33)21-12-20-37-22-19-35-26(37)3/h4-11,13-19,22-23,25H,12,20-21,24H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	689	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair