BDBM50019977 CHEMBL3287828

SMILES: Clc1ccc(NC(=N)c2cccs2)cc1CSC1CCCC1

InChI Key: InChIKey=DSJGZGZLLJYVLQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50019977   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GPR103 (Homo sapiens (Human))	BDBM50019977 (CHEMBL3287828) Show SMILES Clc1ccc(NC(=N)c2cccs2)cc1CSC1CCCC1 Show InChI InChI=1S/C17H19ClN2S2/c18-15-8-7-13(20-17(19)16-6-3-9-21-16)10-12(15)11-22-14-4-1-2-5-14/h3,6-10,14H,1-2,4-5,11H2,(H2,19,20)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at human GPR103 receptor assessed as inhibition of inositol-1-phosphate production by cell-based assay				ACS Med Chem Lett 5: 527-32 (2014) Article DOI: 10.1021/ml400519h BindingDB Entry DOI: 10.7270/Q2V989NR
					More data for this Ligand-Target Pair
GPR103 (Homo sapiens (Human))	BDBM50019977 (CHEMBL3287828) Show SMILES Clc1ccc(NC(=N)c2cccs2)cc1CSC1CCCC1 Show InChI InChI=1S/C17H19ClN2S2/c18-15-8-7-13(20-17(19)16-6-3-9-21-16)10-12(15)11-22-14-4-1-2-5-14/h3,6-10,14H,1-2,4-5,11H2,(H2,19,20)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]-QRFP43 from human GPR103 receptor overexpressed in HEK membranes after 90 mins by liquid scintillation counting				ACS Med Chem Lett 5: 527-32 (2014) Article DOI: 10.1021/ml400519h BindingDB Entry DOI: 10.7270/Q2V989NR
					More data for this Ligand-Target Pair