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SMILES: O=C(Nc1ccccc1)N1CCOc2cc(ccc12)-c1ccc(cc1)[C@H]1CC[C@H](Cc2nnn[nH]2)CC1

InChI Key: InChIKey=BDFNWCJWLVVMQD-MEMLXQNLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50020059   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50020059 (CHEMBL3287887) Show SMILES O=C(Nc1ccccc1)N1CCOc2cc(ccc12)-c1ccc(cc1)[C@H]1CC[C@H](Cc2nnn[nH]2)CC1 |r,wU:25.28,wD:28.32,(8.34,-16.89,;6.99,-16.15,;5.67,-16.95,;5.71,-18.49,;4.39,-19.28,;4.43,-20.82,;5.78,-21.56,;7.1,-20.75,;7.05,-19.22,;6.95,-14.61,;5.6,-13.87,;5.56,-12.33,;6.88,-11.53,;8.23,-12.27,;9.55,-11.47,;10.9,-12.21,;10.93,-13.75,;9.62,-14.55,;8.27,-13.81,;12.21,-11.41,;13.56,-12.15,;14.87,-11.35,;14.84,-9.81,;13.49,-9.07,;12.17,-9.87,;16.15,-9.01,;16.11,-7.47,;17.43,-6.67,;18.78,-7.41,;20.1,-6.61,;21.45,-7.34,;22.83,-6.68,;23.88,-7.79,;23.15,-9.14,;21.64,-8.86,;18.82,-8.95,;17.51,-9.75,)| Show InChI InChI=1S/C29H30N6O2/c36-29(30-25-4-2-1-3-5-25)35-16-17-37-27-19-24(14-15-26(27)35)23-12-10-22(11-13-23)21-8-6-20(7-9-21)18-28-31-33-34-32-28/h1-5,10-15,19-21H,6-9,16-18H2,(H,30,36)(H,31,32,33,34)/t20-,21-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human DGAT1 expressed in Sf9 insect cells using 1,2-dioleoyl-sn-glycerol and [14C]-palmitoyl-CoA substrate by scintillation counting an...				ACS Med Chem Lett 5: 544-9 (2014) Article DOI: 10.1021/ml400527n BindingDB Entry DOI: 10.7270/Q2KS6T3C
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM50020059 (CHEMBL3287887) Show SMILES O=C(Nc1ccccc1)N1CCOc2cc(ccc12)-c1ccc(cc1)[C@H]1CC[C@H](Cc2nnn[nH]2)CC1 |r,wU:25.28,wD:28.32,(8.34,-16.89,;6.99,-16.15,;5.67,-16.95,;5.71,-18.49,;4.39,-19.28,;4.43,-20.82,;5.78,-21.56,;7.1,-20.75,;7.05,-19.22,;6.95,-14.61,;5.6,-13.87,;5.56,-12.33,;6.88,-11.53,;8.23,-12.27,;9.55,-11.47,;10.9,-12.21,;10.93,-13.75,;9.62,-14.55,;8.27,-13.81,;12.21,-11.41,;13.56,-12.15,;14.87,-11.35,;14.84,-9.81,;13.49,-9.07,;12.17,-9.87,;16.15,-9.01,;16.11,-7.47,;17.43,-6.67,;18.78,-7.41,;20.1,-6.61,;21.45,-7.34,;22.83,-6.68,;23.88,-7.79,;23.15,-9.14,;21.64,-8.86,;18.82,-8.95,;17.51,-9.75,)| Show InChI InChI=1S/C29H30N6O2/c36-29(30-25-4-2-1-3-5-25)35-16-17-37-27-19-24(14-15-26(27)35)23-12-10-22(11-13-23)21-8-6-20(7-9-21)18-28-31-33-34-32-28/h1-5,10-15,19-21H,6-9,16-18H2,(H,30,36)(H,31,32,33,34)/t20-,21-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of mouse DGAT1 expressed in Sf9 insect cells using 1,2-dioleoyl-sn-glycerol and [14C]-palmitoyl-CoA substrate by scintillation counting an...				ACS Med Chem Lett 5: 544-9 (2014) Article DOI: 10.1021/ml400527n BindingDB Entry DOI: 10.7270/Q2KS6T3C
					More data for this Ligand-Target Pair