null

SMILES: OC(=O)C[C@H]1CC[C@@H](CC1)c1ccc(cc1)-c1ccc2N(CCOc2n1)C(=O)Nc1ccccc1

InChI Key: InChIKey=SDCUHXDTXXRZJY-MXVIHJGJSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50020068   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50020068 (CHEMBL3287861) Show SMILES OC(=O)C[C@H]1CC[C@@H](CC1)c1ccc(cc1)-c1ccc2N(CCOc2n1)C(=O)Nc1ccccc1 |r,wU:7.10,wD:4.3,(22.48,-9.66,;20.94,-9.66,;20.17,-10.99,;20.17,-8.32,;18.63,-8.32,;17.86,-6.99,;16.32,-6.99,;15.55,-8.32,;16.32,-9.66,;17.86,-9.66,;14.01,-8.32,;13.24,-9.66,;11.7,-9.66,;10.93,-8.32,;11.7,-6.99,;13.24,-6.99,;9.39,-8.32,;8.62,-6.99,;7.08,-6.99,;6.31,-8.32,;4.77,-8.32,;4,-9.66,;4.77,-10.99,;6.31,-10.99,;7.08,-9.66,;8.62,-9.66,;4,-6.99,;4.77,-5.65,;2.46,-6.99,;1.69,-5.65,;.15,-5.65,;-.62,-4.32,;.15,-2.99,;1.69,-2.99,;2.46,-4.32,)| Show InChI InChI=1S/C28H29N3O4/c32-26(33)18-19-6-8-20(9-7-19)21-10-12-22(13-11-21)24-14-15-25-27(30-24)35-17-16-31(25)28(34)29-23-4-2-1-3-5-23/h1-5,10-15,19-20H,6-9,16-18H2,(H,29,34)(H,32,33)/t19-,20-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human DGAT1 expressed in Sf9 insect cells using 1,2-dioleoyl-sn-glycerol and [14C]-palmitoyl-CoA substrate by scintillation counting an...				ACS Med Chem Lett 5: 544-9 (2014) Article DOI: 10.1021/ml400527n BindingDB Entry DOI: 10.7270/Q2KS6T3C
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM50020068 (CHEMBL3287861) Show SMILES OC(=O)C[C@H]1CC[C@@H](CC1)c1ccc(cc1)-c1ccc2N(CCOc2n1)C(=O)Nc1ccccc1 |r,wU:7.10,wD:4.3,(22.48,-9.66,;20.94,-9.66,;20.17,-10.99,;20.17,-8.32,;18.63,-8.32,;17.86,-6.99,;16.32,-6.99,;15.55,-8.32,;16.32,-9.66,;17.86,-9.66,;14.01,-8.32,;13.24,-9.66,;11.7,-9.66,;10.93,-8.32,;11.7,-6.99,;13.24,-6.99,;9.39,-8.32,;8.62,-6.99,;7.08,-6.99,;6.31,-8.32,;4.77,-8.32,;4,-9.66,;4.77,-10.99,;6.31,-10.99,;7.08,-9.66,;8.62,-9.66,;4,-6.99,;4.77,-5.65,;2.46,-6.99,;1.69,-5.65,;.15,-5.65,;-.62,-4.32,;.15,-2.99,;1.69,-2.99,;2.46,-4.32,)| Show InChI InChI=1S/C28H29N3O4/c32-26(33)18-19-6-8-20(9-7-19)21-10-12-22(13-11-21)24-14-15-25-27(30-24)35-17-16-31(25)28(34)29-23-4-2-1-3-5-23/h1-5,10-15,19-20H,6-9,16-18H2,(H,29,34)(H,32,33)/t19-,20-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of mouse DGAT1 expressed in Sf9 insect cells using 1,2-dioleoyl-sn-glycerol and [14C]-palmitoyl-CoA substrate by scintillation counting an...				ACS Med Chem Lett 5: 544-9 (2014) Article DOI: 10.1021/ml400527n BindingDB Entry DOI: 10.7270/Q2KS6T3C
					More data for this Ligand-Target Pair