BDBM50020076 CHEMBL3287880

SMILES: Nc1ccccc1NC(=O)N1CCOc2cc(ccc12)-c1ccc(cc1)[C@H]1CC[C@H](CC(O)=O)CC1

InChI Key: InChIKey=FWDYUZARYCUJFL-MXVIHJGJSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50020076   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human))	BDBM50020076 (CHEMBL3287880) Show SMILES Nc1ccccc1NC(=O)N1CCOc2cc(ccc12)-c1ccc(cc1)[C@H]1CC[C@H](CC(O)=O)CC1 |r,wU:29.33,wD:26.29,(2.65,-29.35,;3.42,-28.02,;2.65,-26.68,;3.42,-25.35,;4.96,-25.35,;5.73,-26.68,;4.96,-28.02,;5.73,-29.35,;7.27,-29.35,;8.04,-28.02,;8.04,-30.68,;7.27,-32.02,;8.04,-33.35,;9.58,-33.35,;10.35,-32.02,;11.89,-32.02,;12.66,-30.68,;11.89,-29.35,;10.35,-29.35,;9.58,-30.68,;14.2,-30.68,;14.97,-32.02,;16.51,-32.02,;17.28,-30.68,;16.51,-29.35,;14.97,-29.35,;18.82,-30.68,;19.59,-32.02,;21.13,-32.02,;21.9,-30.68,;23.44,-30.68,;24.21,-32.02,;23.44,-33.35,;25.75,-32.02,;21.13,-29.35,;19.59,-29.35,)| Show InChI InChI=1S/C29H31N3O4/c30-24-3-1-2-4-25(24)31-29(35)32-15-16-36-27-18-23(13-14-26(27)32)22-11-9-21(10-12-22)20-7-5-19(6-8-20)17-28(33)34/h1-4,9-14,18-20H,5-8,15-17,30H2,(H,31,35)(H,33,34)/t19-,20-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human DGAT1 expressed in Sf9 insect cells using 1,2-dioleoyl-sn-glycerol and [14C]-palmitoyl-CoA substrate by scintillation counting an...				ACS Med Chem Lett 5: 544-9 (2014) Article DOI: 10.1021/ml400527n BindingDB Entry DOI: 10.7270/Q2KS6T3C
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM50020076 (CHEMBL3287880) Show SMILES Nc1ccccc1NC(=O)N1CCOc2cc(ccc12)-c1ccc(cc1)[C@H]1CC[C@H](CC(O)=O)CC1 |r,wU:29.33,wD:26.29,(2.65,-29.35,;3.42,-28.02,;2.65,-26.68,;3.42,-25.35,;4.96,-25.35,;5.73,-26.68,;4.96,-28.02,;5.73,-29.35,;7.27,-29.35,;8.04,-28.02,;8.04,-30.68,;7.27,-32.02,;8.04,-33.35,;9.58,-33.35,;10.35,-32.02,;11.89,-32.02,;12.66,-30.68,;11.89,-29.35,;10.35,-29.35,;9.58,-30.68,;14.2,-30.68,;14.97,-32.02,;16.51,-32.02,;17.28,-30.68,;16.51,-29.35,;14.97,-29.35,;18.82,-30.68,;19.59,-32.02,;21.13,-32.02,;21.9,-30.68,;23.44,-30.68,;24.21,-32.02,;23.44,-33.35,;25.75,-32.02,;21.13,-29.35,;19.59,-29.35,)| Show InChI InChI=1S/C29H31N3O4/c30-24-3-1-2-4-25(24)31-29(35)32-15-16-36-27-18-23(13-14-26(27)32)22-11-9-21(10-12-22)20-7-5-19(6-8-20)17-28(33)34/h1-4,9-14,18-20H,5-8,15-17,30H2,(H,31,35)(H,33,34)/t19-,20-	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of mouse DGAT1 expressed in Sf9 insect cells using 1,2-dioleoyl-sn-glycerol and [14C]-palmitoyl-CoA substrate by scintillation counting an...				ACS Med Chem Lett 5: 544-9 (2014) Article DOI: 10.1021/ml400527n BindingDB Entry DOI: 10.7270/Q2KS6T3C
					More data for this Ligand-Target Pair