null

SMILES: OC(=O)C[C@H]1CC[C@@H](CC1)c1ccc(cc1)-c1cccc2N(CCOc12)C(=O)Nc1ccccc1

InChI Key: InChIKey=DALSSRBLGSHFQN-MEMLXQNLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50020078   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM50020078 (CHEMBL3287858) Show SMILES OC(=O)C[C@H]1CC[C@@H](CC1)c1ccc(cc1)-c1cccc2N(CCOc12)C(=O)Nc1ccccc1 |r,wU:7.10,wD:4.3,(19.28,3.4,;17.95,2.63,;16.62,3.4,;17.95,1.09,;16.62,.32,;15.28,1.09,;13.95,.32,;13.95,-1.22,;15.28,-1.99,;16.62,-1.22,;12.62,-1.99,;12.62,-3.53,;11.28,-4.3,;9.95,-3.53,;9.95,-1.99,;11.28,-1.22,;8.62,-4.3,;7.28,-3.53,;5.95,-4.3,;5.95,-5.84,;7.28,-6.61,;7.28,-8.15,;8.62,-8.92,;9.95,-8.15,;9.95,-6.61,;8.62,-5.84,;5.95,-8.92,;4.61,-8.15,;5.95,-10.46,;4.61,-11.23,;4.61,-12.77,;3.28,-13.54,;1.95,-12.77,;1.95,-11.23,;3.28,-10.46,)| Show InChI InChI=1S/C29H30N2O4/c32-27(33)19-20-9-11-21(12-10-20)22-13-15-23(16-14-22)25-7-4-8-26-28(25)35-18-17-31(26)29(34)30-24-5-2-1-3-6-24/h1-8,13-16,20-21H,9-12,17-19H2,(H,30,34)(H,32,33)/t20-,21-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of mouse DGAT1 expressed in Sf9 insect cells using 1,2-dioleoyl-sn-glycerol and [14C]-palmitoyl-CoA substrate by scintillation counting an...				ACS Med Chem Lett 5: 544-9 (2014) Article DOI: 10.1021/ml400527n BindingDB Entry DOI: 10.7270/Q2KS6T3C
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50020078 (CHEMBL3287858) Show SMILES OC(=O)C[C@H]1CC[C@@H](CC1)c1ccc(cc1)-c1cccc2N(CCOc12)C(=O)Nc1ccccc1 |r,wU:7.10,wD:4.3,(19.28,3.4,;17.95,2.63,;16.62,3.4,;17.95,1.09,;16.62,.32,;15.28,1.09,;13.95,.32,;13.95,-1.22,;15.28,-1.99,;16.62,-1.22,;12.62,-1.99,;12.62,-3.53,;11.28,-4.3,;9.95,-3.53,;9.95,-1.99,;11.28,-1.22,;8.62,-4.3,;7.28,-3.53,;5.95,-4.3,;5.95,-5.84,;7.28,-6.61,;7.28,-8.15,;8.62,-8.92,;9.95,-8.15,;9.95,-6.61,;8.62,-5.84,;5.95,-8.92,;4.61,-8.15,;5.95,-10.46,;4.61,-11.23,;4.61,-12.77,;3.28,-13.54,;1.95,-12.77,;1.95,-11.23,;3.28,-10.46,)| Show InChI InChI=1S/C29H30N2O4/c32-27(33)19-20-9-11-21(12-10-20)22-13-15-23(16-14-22)25-7-4-8-26-28(25)35-18-17-31(26)29(34)30-24-5-2-1-3-6-24/h1-8,13-16,20-21H,9-12,17-19H2,(H,30,34)(H,32,33)/t20-,21-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human DGAT1 expressed in Sf9 insect cells using 1,2-dioleoyl-sn-glycerol and [14C]-palmitoyl-CoA substrate by scintillation counting an...				ACS Med Chem Lett 5: 544-9 (2014) Article DOI: 10.1021/ml400527n BindingDB Entry DOI: 10.7270/Q2KS6T3C
					More data for this Ligand-Target Pair