BDBM50020109 2-{4-[(2-Amino-4-oxo-1,4,5,6,7,8-hexahydro-pteridin-6-ylmethyl)-amino]-benzoylamino}-4-carbamoyl-butyric acid::CHEMBL25870

SMILES: NC(=O)CC[C@H](NC(=O)c1ccc(NCC2CNc3nc(N)[nH]c(=O)c3N2)cc1)C(O)=O

InChI Key: InChIKey=GIPGZOYCBZBYHG-KIYNQFGBSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50020109   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Folylpoly-gamma-glutamate synthetase (Homo sapiens (Human))	BDBM50020109 (2-{4-[(2-Amino-4-oxo-1,4,5,6,7,8-hexahydro-pteridi...) Show SMILES NC(=O)CC[C@H](NC(=O)c1ccc(NCC2CNc3nc(N)[nH]c(=O)c3N2)cc1)C(O)=O Show InChI InChI=1S/C19H24N8O5/c20-13(28)6-5-12(18(31)32)25-16(29)9-1-3-10(4-2-9)22-7-11-8-23-15-14(24-11)17(30)27-19(21)26-15/h1-4,11-12,22,24H,5-8H2,(H2,20,28)(H,25,29)(H,31,32)(H4,21,23,26,27,30)/t11?,12-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibitory constant against purified Folyl-polyglutamate synthase obtained from hog				J Med Chem 31: 1338-44 (1988) BindingDB Entry DOI: 10.7270/Q22J6CFD
					More data for this Ligand-Target Pair