BDBM50020620 CHEMBL3290470

SMILES: NC(=O)c1cccc2C(=O)\C(Oc12)=C\c1ccc(Cl)cc1

InChI Key: InChIKey=FGZBIWIBURSQSP-JYRVWZFOSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50020620   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50020620 (CHEMBL3290470) Show SMILES NC(=O)c1cccc2C(=O)\C(Oc12)=C\c1ccc(Cl)cc1 Show InChI InChI=1S/C16H10ClNO3/c17-10-6-4-9(5-7-10)8-13-14(19)11-2-1-3-12(16(18)20)15(11)21-13/h1-8H,(H2,18,20)/b13-8-	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
St. John's University Curated by ChEMBL					Assay Description Inhibition of PARP-1 (unknown origin) using biotinylated NAD+ as substrate after 60 mins by spectrophotometry				J Med Chem 57: 5579-601 (2014) Article DOI: 10.1021/jm5002502 BindingDB Entry DOI: 10.7270/Q28C9XSS
					More data for this Ligand-Target Pair