BDBM50020659 CHEMBL3290498
SMILES: [H][C@@]1(O[C@]1(C)[C@@]1([H])[C@@H](\C=C\C=C\C=C\C(O)=O)[C@]2([H])CC=C(C)C[C@@]2([H])C=C1C)[C@H](C)CC
InChI Key: InChIKey=GEGSNPGPRRSEET-YWHCRWFKSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA polymerase beta (Rattus norvegicus) | BDBM50020659 (CHEMBL3290498) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of rat recombinant DNA polymerase beta expressed in Escherichia coli JMpbeta5 cells assessed as incorporation of [3H]dTTP into poly(dA)/ol... | J Nat Prod 77: 1404-12 (2014) Article DOI: 10.1021/np500143k BindingDB Entry DOI: 10.7270/Q24M9639 | |||||||||||
More data for this Ligand-Target Pair |