BDBM50020863 CHEMBL3286986
SMILES: COc1cc(\C=c2/sc3nc(cn3c2=O)-c2ccncc2C)ccc1O
InChI Key: InChIKey=LLBFVGVUIRTOHO-IUXPMGMMSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta amyloid A4 protein (Homo sapiens (Human)) | BDBM50020863 (CHEMBL3286986) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University School of Pharmacy Curated by ChEMBL | Assay Description Inhibition of amyloid beta (unknown origin) aggregation by Thiazin-red R displacement fluorescence assay | ACS Med Chem Lett 5: 619-20 (2014) Article DOI: 10.1021/ml500147n BindingDB Entry DOI: 10.7270/Q2ZW1NGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tau (Homo sapiens (Human)) | BDBM50020863 (CHEMBL3286986) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 79 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University School of Pharmacy Curated by ChEMBL | Assay Description Inhibition of recombinant human microtubule associated protein tau aggregation by Thiazin-red R displacement fluorescence assay | ACS Med Chem Lett 5: 619-20 (2014) Article DOI: 10.1021/ml500147n BindingDB Entry DOI: 10.7270/Q2ZW1NGS | |||||||||||
More data for this Ligand-Target Pair |