BDBM50021546 4-Fluoro-3-(1-hydroxy-2-methylamino-ethyl)-phenol::4-Fluoro-3-(1-hydroxy-2-methylamino-ethyl)-phenol(6-FPE)::CHEMBL61372
SMILES: CNCC(O)c1cc(O)ccc1F
InChI Key: InChIKey=YTBMWHRBVZXATF-UHFFFAOYSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Adrenergic receptor alpha-2 (Homo sapiens (Human)) | BDBM50021546 (4-Fluoro-3-(1-hydroxy-2-methylamino-ethyl)-phenol ...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for its ability to displace [3H]clonidine form alpha-2 adrenergic receptor site in guinea pig cerebral cortical membranes. | J Med Chem 29: 1982-8 (1986) BindingDB Entry DOI: 10.7270/Q24M96QC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50021546 (4-Fluoro-3-(1-hydroxy-2-methylamino-ethyl)-phenol ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Displacement of [3H]clonidine from adrenergic alpha 2 receptor of rat cerebral cortical membranes | J Med Chem 36: 3947-55 (1994) BindingDB Entry DOI: 10.7270/Q2QC044C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50021546 (4-Fluoro-3-(1-hydroxy-2-methylamino-ethyl)-phenol ...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Displacement of [3H]WB-4101 from adrenergic alpha 1 receptor of rat cerebral cortical membranes | J Med Chem 36: 3947-55 (1994) BindingDB Entry DOI: 10.7270/Q2QC044C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50021546 (4-Fluoro-3-(1-hydroxy-2-methylamino-ethyl)-phenol ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Displacement of [3H]dihydroalprenolol from adrenergic beta 1 receptor of rat cerebral cortical membranes | J Med Chem 36: 3947-55 (1994) BindingDB Entry DOI: 10.7270/Q2QC044C | |||||||||||
More data for this Ligand-Target Pair |