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SMILES: COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5ccc(Cl)cc5Cl)c(=O)cc4C)cc3F)ccnc2cc1OCCCN1CCC(C)CC1

InChI Key: InChIKey=ILBWPLNUEWTSFN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50021569   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50021569
PNG
(CHEMBL3290899)
Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5ccc(Cl)cc5Cl)c(=O)cc4C)cc3F)ccnc2cc1OCCCN1CCC(C)CC1
Show InChI InChI=1S/C37H36Cl2FN5O5/c1-22-10-14-44(15-11-22)13-4-16-49-34-21-29-26(20-33(34)48-3)31(9-12-41-29)50-32-8-6-25(19-28(32)40)42-37(47)36-23(2)17-35(46)45(43-36)30-7-5-24(38)18-27(30)39/h5-9,12,17-22H,4,10-11,13-16H2,1-3H3,(H,42,47)
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Similars
Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate by homogeneous time-resolved fluorescence assay

Eur J Med Chem 83: 581-93 (2014)


Article DOI: 10.1016/j.ejmech.2014.06.068
BindingDB Entry DOI: 10.7270/Q2R78GTF
More data for this
Ligand-Target Pair