BDBM50021631 CHEMBL3298659

SMILES: CC(C)(C)CNC(=O)CC1CNC(=O)c2cc(cn12)-c1cccc(F)c1

InChI Key: InChIKey=ZYQVJKVDYJSBES-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50021631   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021631 (CHEMBL3298659) Show SMILES CC(C)(C)CNC(=O)CC1CNC(=O)c2cc(cn12)-c1cccc(F)c1 Show InChI InChI=1S/C20H24FN3O2/c1-20(2,3)12-23-18(25)9-16-10-22-19(26)17-8-14(11-24(16)17)13-5-4-6-15(21)7-13/h4-8,11,16H,9-10,12H2,1-3H3,(H,22,26)(H,23,25)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair