BDBM50021635 CHEMBL3298564

SMILES: Fc1cccc(CNC(=O)CC2CNC(=O)c3cc(cn23)-c2cccc(c2)C(F)(F)F)c1

InChI Key: InChIKey=YCASZMQQNSTXQF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50021635   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50021635 (CHEMBL3298564) Show SMILES Fc1cccc(CNC(=O)CC2CNC(=O)c3cc(cn23)-c2cccc(c2)C(F)(F)F)c1 Show InChI InChI=1S/C23H19F4N3O2/c24-18-6-1-3-14(7-18)11-28-21(31)10-19-12-29-22(32)20-9-16(13-30(19)20)15-4-2-5-17(8-15)23(25,26)27/h1-9,13,19H,10-12H2,(H,28,31)(H,29,32)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021635 (CHEMBL3298564) Show SMILES Fc1cccc(CNC(=O)CC2CNC(=O)c3cc(cn23)-c2cccc(c2)C(F)(F)F)c1 Show InChI InChI=1S/C23H19F4N3O2/c24-18-6-1-3-14(7-18)11-28-21(31)10-19-12-29-22(32)20-9-16(13-30(19)20)15-4-2-5-17(8-15)23(25,26)27/h1-9,13,19H,10-12H2,(H,28,31)(H,29,32)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	614	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair