BDBM50021640 CHEMBL3298821

SMILES: Fc1ccc(cc1F)-c1cc2C(=O)NCC(CC(=O)NCC3CCCCC3)n2c1

InChI Key: InChIKey=SGXRBZAUSKURHK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50021640   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50021640 (CHEMBL3298821) Show SMILES Fc1ccc(cc1F)-c1cc2C(=O)NCC(CC(=O)NCC3CCCCC3)n2c1 Show InChI InChI=1S/C22H25F2N3O2/c23-18-7-6-15(8-19(18)24)16-9-20-22(29)26-12-17(27(20)13-16)10-21(28)25-11-14-4-2-1-3-5-14/h6-9,13-14,17H,1-5,10-12H2,(H,25,28)(H,26,29)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021640 (CHEMBL3298821) Show SMILES Fc1ccc(cc1F)-c1cc2C(=O)NCC(CC(=O)NCC3CCCCC3)n2c1 Show InChI InChI=1S/C22H25F2N3O2/c23-18-7-6-15(8-19(18)24)16-9-20-22(29)26-12-17(27(20)13-16)10-21(28)25-11-14-4-2-1-3-5-14/h6-9,13-14,17H,1-5,10-12H2,(H,25,28)(H,26,29)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair