BDBM50021642 CHEMBL3298824

SMILES: Fc1ccc(cc1F)-c1cc2C(=O)NCC(CC(=O)NCc3ccco3)n2c1

InChI Key: InChIKey=RDHJWXPEAUFUNK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50021642   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50021642 (CHEMBL3298824) Show SMILES Fc1ccc(cc1F)-c1cc2C(=O)NCC(CC(=O)NCc3ccco3)n2c1 Show InChI InChI=1S/C20H17F2N3O3/c21-16-4-3-12(6-17(16)22)13-7-18-20(27)24-9-14(25(18)11-13)8-19(26)23-10-15-2-1-5-28-15/h1-7,11,14H,8-10H2,(H,23,26)(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021642 (CHEMBL3298824) Show SMILES Fc1ccc(cc1F)-c1cc2C(=O)NCC(CC(=O)NCc3ccco3)n2c1 Show InChI InChI=1S/C20H17F2N3O3/c21-16-4-3-12(6-17(16)22)13-7-18-20(27)24-9-14(25(18)11-13)8-19(26)23-10-15-2-1-5-28-15/h1-7,11,14H,8-10H2,(H,23,26)(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	125	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair