BDBM50021652 CHEMBL3297758

SMILES: OC[C@H](Cc1ccccc1)NC(=O)C[C@H]1CNC(=O)c2cc(cn12)-c1cccc(F)c1

InChI Key: InChIKey=AFHADFMYZXZAEV-SFTDATJTSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50021652   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50021652 (CHEMBL3297758) Show SMILES OC[C@H](Cc1ccccc1)NC(=O)C[C@H]1CNC(=O)c2cc(cn12)-c1cccc(F)c1 |r| Show InChI InChI=1S/C24H24FN3O3/c25-19-8-4-7-17(10-19)18-11-22-24(31)26-13-21(28(22)14-18)12-23(30)27-20(15-29)9-16-5-2-1-3-6-16/h1-8,10-11,14,20-21,29H,9,12-13,15H2,(H,26,31)(H,27,30)/t20-,21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	684	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021652 (CHEMBL3297758) Show SMILES OC[C@H](Cc1ccccc1)NC(=O)C[C@H]1CNC(=O)c2cc(cn12)-c1cccc(F)c1 |r| Show InChI InChI=1S/C24H24FN3O3/c25-19-8-4-7-17(10-19)18-11-22-24(31)26-13-21(28(22)14-18)12-23(30)27-20(15-29)9-16-5-2-1-3-6-16/h1-8,10-11,14,20-21,29H,9,12-13,15H2,(H,26,31)(H,27,30)/t20-,21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	141	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair