BDBM50021654 CHEMBL3297760

SMILES: CN1CCN([C@H](C1)c1ccccc1)C(=O)C[C@H]1CNC(=O)c2cc(cn12)-c1cccc(F)c1

InChI Key: InChIKey=MZBVCDVHYWIHEK-LADGPHEKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50021654   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50021654 (CHEMBL3297760) Show SMILES CN1CCN([C@H](C1)c1ccccc1)C(=O)C[C@H]1CNC(=O)c2cc(cn12)-c1cccc(F)c1 |r| Show InChI InChI=1S/C26H27FN4O2/c1-29-10-11-30(24(17-29)18-6-3-2-4-7-18)25(32)14-22-15-28-26(33)23-13-20(16-31(22)23)19-8-5-9-21(27)12-19/h2-9,12-13,16,22,24H,10-11,14-15,17H2,1H3,(H,28,33)/t22-,24+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	956	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021654 (CHEMBL3297760) Show SMILES CN1CCN([C@H](C1)c1ccccc1)C(=O)C[C@H]1CNC(=O)c2cc(cn12)-c1cccc(F)c1 |r| Show InChI InChI=1S/C26H27FN4O2/c1-29-10-11-30(24(17-29)18-6-3-2-4-7-18)25(32)14-22-15-28-26(33)23-13-20(16-31(22)23)19-8-5-9-21(27)12-19/h2-9,12-13,16,22,24H,10-11,14-15,17H2,1H3,(H,28,33)/t22-,24+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	233	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair