null

SMILES: COc1ccc(Nc2nc3cccc(-c4c(F)cccc4OC)c3o2)cc1N

InChI Key: InChIKey=AATRJMCVLUZFSH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50021667   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50021667 (CHEMBL3297950) Show SMILES COc1ccc(Nc2nc3cccc(-c4c(F)cccc4OC)c3o2)cc1N |(11.58,-23.49,;13.12,-23.49,;13.89,-22.16,;13.12,-20.82,;13.9,-19.49,;15.44,-19.49,;16.21,-18.16,;17.75,-18.16,;18.66,-16.92,;20.12,-17.4,;21.45,-16.62,;22.78,-17.38,;22.79,-18.93,;21.45,-19.71,;21.46,-21.25,;20.13,-22.02,;18.79,-21.25,;20.12,-23.56,;21.46,-24.33,;22.8,-23.55,;22.79,-22.02,;24.12,-21.24,;25.46,-22,;20.12,-18.94,;18.65,-19.41,;16.21,-20.82,;15.44,-22.15,;16.21,-23.49,)| Show InChI InChI=1S/C21H18FN3O3/c1-26-17-10-9-12(11-15(17)23)24-21-25-16-7-3-5-13(20(16)28-21)19-14(22)6-4-8-18(19)27-2/h3-11H,23H2,1-2H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of RSK2 in mouse BAF cells assessed as YB1 phosphorylation at Ser102 by electrochemiluminescence assay				Bioorg Med Chem Lett 24: 1592-6 (2014) Article DOI: 10.1016/j.bmcl.2014.01.058 BindingDB Entry DOI: 10.7270/Q2V126DB
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50021667 (CHEMBL3297950) Show SMILES COc1ccc(Nc2nc3cccc(-c4c(F)cccc4OC)c3o2)cc1N |(11.58,-23.49,;13.12,-23.49,;13.89,-22.16,;13.12,-20.82,;13.9,-19.49,;15.44,-19.49,;16.21,-18.16,;17.75,-18.16,;18.66,-16.92,;20.12,-17.4,;21.45,-16.62,;22.78,-17.38,;22.79,-18.93,;21.45,-19.71,;21.46,-21.25,;20.13,-22.02,;18.79,-21.25,;20.12,-23.56,;21.46,-24.33,;22.8,-23.55,;22.79,-22.02,;24.12,-21.24,;25.46,-22,;20.12,-18.94,;18.65,-19.41,;16.21,-20.82,;15.44,-22.15,;16.21,-23.49,)| Show InChI InChI=1S/C21H18FN3O3/c1-26-17-10-9-12(11-15(17)23)24-21-25-16-7-3-5-13(20(16)28-21)19-14(22)6-4-8-18(19)27-2/h3-11H,23H2,1-2H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant full length RSK2 (unknown origin) using biotin-AGAGRSRHSSYPAGT-OH as substrate after 150 mins				Bioorg Med Chem Lett 24: 1592-6 (2014) Article DOI: 10.1016/j.bmcl.2014.01.058 BindingDB Entry DOI: 10.7270/Q2V126DB
					More data for this Ligand-Target Pair